When the temperature drops, people with autoimmune diseases often feel it before the forecast even updates. That stiff ache in the joints, the sudden fatigue, or that “I just can’t get warm” sensation — all too familiar for those managing chronic inflammatory conditions. According to Science Direct, environmental changes like humidity shifts, shorter daylight hours, and cold exposure can dramatically influence immune and inflammatory responses. For many Americans living with lupus, rheumatoid arthritis (RA), or multiple sclerosis (MS), winter isn’t just about hot cocoa and cozy blankets — it’s a season that tests both their physical resilience and work-life balance.
At My Dr’s Note, we understand how unpredictable autoimmune flare-ups can be, especially when they interfere with work attendance or daily functioning. Let’s unpack what happens in your body during cold months, why flare-ups spike, and how to navigate time off responsibly while protecting your health.
Why Winter Makes Autoimmune Symptoms Worse
The science is clear — cold temperatures impact circulation, muscle tension, and immune function. In autoimmune diseases, where the body’s defense system mistakenly attacks healthy tissue, these factors can amplify inflammation.
For instance, colder environments can restrict blood flow, leading to joint stiffness and pain in rheumatoid arthritis. Meanwhile, low sunlight exposure means reduced vitamin D synthesis, which plays a key role in immune regulation. When vitamin D levels drop, inflammatory pathways may become more active, triggering symptom flare-ups.
For people with lupus, the cold also brings changes in microcirculation, which can worsen Raynaud’s phenomenon — a common complication that causes fingers or toes to turn white or blue due to poor blood flow. And for those with MS, lower temperatures may not worsen the disease itself, but fatigue, numbness, or muscle weakness can intensify, making daily work tasks more difficult.
Lupus and Winter: When the Cold Becomes an Adversary
Lupus patients often describe winter as their least favorite season — not just because of the chill, but because of what it does to their immune balance. In addition to temperature sensitivity, lupus is highly influenced by stress and infection, both of which spike in colder months when flu and RSV are more prevalent.
Flare-ups can bring on joint pain, fatigue, and fever-like symptoms that make attending work nearly impossible. Studies have shown that people with systemic lupus often experience a pattern of “flares and remission,” where stress and environmental triggers can turn a good day into a bed-bound one.
When that happens, it’s crucial not to push through illness. Continuing to work through severe fatigue or pain can prolong recovery and increase inflammation. This is where requesting a doctor’s note for work becomes important — not as an excuse, but as a necessary form of protection for your health and your employment record.
Rheumatoid Arthritis and the Temperature Connection
Rheumatoid arthritis (RA) is an autoimmune condition that causes the body to attack its own joint lining, leading to swelling, stiffness, and chronic pain. Research has found that people with RA report increased joint stiffness and fatigue during winter months — not only because of the cold, but also due to atmospheric pressure changes and decreased physical activity.
When the barometric pressure drops, tissues in the joints expand slightly, pressing on nerves and intensifying discomfort. Combine that with shorter days, less sunlight, and more sedentary hours indoors, and flare-ups can quickly spiral.

Employers may not always understand how variable RA can be — one day you might manage tasks perfectly, and the next, typing or lifting can be excruciating. Having access to a real doctor’s note for work provides a legitimate way to explain absences without risking disciplinary action or misunderstandings. It also validates your condition in a professional, medically supported manner.
Multiple Sclerosis: Cold Sensitivity and Fatigue
While heat sensitivity is often discussed in multiple sclerosis, many individuals also report that extreme cold aggravates muscle stiffness and fatigue. The drop in temperature can affect nerve conduction, making it harder for muscles to respond.
Winter infections such as influenza or COVID-19 can also worsen MS symptoms temporarily — a phenomenon known as a “pseudo-relapse.” These episodes mimic real relapses, but they’re triggered by external stressors like illness or fever.
Because MS symptoms vary so widely (from numbness and cognitive fog to balance issues), employees with this condition often need flexible schedules or remote work options during cold months. An online doctor’s note for work can help formalize such accommodations and prevent conflicts with supervisors or HR departments.
The Emotional Toll of Winter Flare-Ups
It’s not just the body that suffers — autoimmune flare-ups often come with a heavy emotional load. Seasonal Affective Disorder (SAD), limited sunlight exposure, and reduced social activity can contribute to anxiety or depression. Chronic pain itself can be isolating, and when combined with workplace pressure to “show up anyway,” it can lead to burnout.
A practical approach involves setting boundaries and recognizing early signs of flare-ups before they spiral. Keep a symptom journal to track triggers like temperature, diet, or stress levels. Incorporate gentle physical activity like yoga or stretching indoors, which helps circulation and joint mobility. And don’t underestimate the value of proper rest — even short absences supported by a doctor’s note online can prevent long-term setbacks.
Managing Work Absences the Smart Way
When autoimmune symptoms flare, communication and documentation are everything. Employers in the U.S. are increasingly aware of chronic illness accommodations, but most still require proper medical documentation to process leave requests.
That’s where My Dr’s Note simplifies things. Instead of waiting days for an appointment or risking unpaid leave, you can get a doctor’s note online after completing a secure assessment. Your symptoms are reviewed by Board-Certified physicians who evaluate whether rest or recovery time is warranted.
For extended absences or recurring flare-ups, you may also qualify for an online FMLA certification. The Family and Medical Leave Act protects eligible employees by allowing them up to 12 weeks of unpaid, job-protected leave annually for medical reasons. This can be crucial for autoimmune patients who experience cyclical flare-ups throughout the year.
Practical Tips to Reduce Flare-Ups This Winter
While autoimmune diseases can’t be cured, lifestyle adjustments can help minimize winter flare-ups and support immune balance:
- Dress smart: Keep joints warm using compression gloves or heated wraps.
- Stay hydrated: Indoor heating dehydrates the body, which can worsen fatigue.
- Eat anti-inflammatory foods: Think leafy greens, turmeric, berries, and omega-3-rich plant sources like flaxseeds and walnuts.
- Manage stress: Practice breathing exercises, meditation, or guided relaxation.
- Prioritize sleep: The immune system repairs itself during rest — treat sleep like medicine.
- Get sunlight exposure: Even brief walks can help regulate vitamin D and serotonin.
By staying proactive, patients can reduce symptom severity and avoid unnecessary absences. But when flare-ups do hit hard, documentation and communication remain your best allies.
Balancing Health and Professional Life
No one should have to choose between keeping a job and protecting their health. Yet many autoimmune patients report guilt or anxiety when requesting time off. That mindset often leads to overworking during flare-ups, which can backfire physically and professionally.
The goal is balance — knowing when to step back and when to push forward. Using a real doctor’s note online through a verified provider like My Dr’s Note gives you peace of mind that your absences are legitimate, confidential, and supported by licensed professionals.
Winter might challenge your immune system, but it doesn’t have to derail your career. With the right strategies — medical documentation, workplace communication, and daily self-care — you can stay functional and protect your long-term wellbeing.
Final Thoughts
Autoimmune flare-ups in winter are not a matter of willpower — they’re a physiological response to temperature, stress, and immune fluctuations. The smartest way to handle them is with preparation, proper documentation, and self-compassion. Take your time to heal, communicate openly with your employer, and don’t hesitate to seek a doctor’s excuse online if you need it. Your body deserves that break, and your future self will thank you for it.
Get a Doctor’s Note Online — Fast and Legit
At My Dr’s Note, we genuinely prioritize your health and recognize the significance of allowing your body time to recuperate in case of illness. Our team consists of Board Certified medical doctors who hold licenses in all 50 states, specializing in Family Medicine and Emergency Medicine. We understand the challenges that arise when trying to schedule appointments or reach out to your doctor for a medical excuse note.
To offer you a simpler alternative, we’ve dedicated our efforts to providing this service through our convenient path to wellness. By signing up and completing our online assessment, you may meet the criteria to receive an authentic online doctor’s note for work, school, or travel — without an appointment.
Your reported symptoms will be reviewed by our Board-Certified physicians. If approved, you’ll receive your online real doctor’s note promptly. We help you focus on battling your illness without stress or worries. We also offer travel cancellation notes, ESA letters, and FMLA-related documentation.
Check out our FAQs for details, or simply call now to connect with our licensed providers and get a real doctor’s note online the same day.